Qishen Huoxue Granule Ameliorates LPS-induced Cardiomyocyte Injuryby Suppressing Excessive Autophagy via MasR/PI3K-AKT-mTORPathway
By inhibiting excessive autophagy through upregulation of the MasR/PI3K-AKTmTOR pathway, QHG can alleviate sepsis-induced cardiomyocyte damage. This study provides novel perspectives for the management of sepsis-induced cardiac damage.
Authors
- Zhaoqing Lu
- Zheng Wang (ORCID: https://orcid.org/0000-0001-9159-047X)
- Huan Tang (ORCID: https://orcid.org/0000-0002-0244-3169)
- Guoxing Wang (ORCID: https://orcid.org/0000-0001-7762-4848)
- Yufan Du
Institutions
- Beijing University of Chinese Medicine (CN)
- Capital Medical University (CN)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-24
- DOI
- https://doi.org/10.2174/0113862073359792250401180222
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00