A Baicalin-targeted ZHX2/MMP14 Axis Attenuates Cirrhotic PortalHypertension
BA up-regulates ZHX2 to reduce the level of MMP14 and alleviate CPH. Understanding the mechanisms of BA in CPH may provide a foundation for novel interventions to attenuate CPH.
Authors
- Xiao Dong Cai
- Yufei Chang (ORCID: https://orcid.org/0000-0001-6137-0329)
- Jiawei Ma (ORCID: https://orcid.org/0000-0002-0596-770X)
- Jinghe Liu (ORCID: https://orcid.org/0000-0002-3017-4816)
- Xiao Liu (ORCID: https://orcid.org/0000-0003-4221-5061)
- Hui Wang (ORCID: https://orcid.org/0000-0002-8549-3398)
Institutions
- Capital Medical University (CN)
- Beijing Ditan Hospital (CN)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2025-04-24
- DOI
- https://doi.org/10.2174/0113892010349745250416105433
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00