Biochemical changes in rats after treatment with soft drink and menthol flavoured candy

The current study looked at the biochemical variations that occurred in rats after they were given menthol flavoured candies and soft drinks. Seventy male Wistar albino rats in total were acquired, split up into ten treatments of seven rats each, and treated with the following regimen for forty-two days. Group 1 is the control. Groups 2, 3, and 4 received 8, 5, and 2.5 ml of La Casera/kg body weight. Groups 5, 6, and 7 received 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight. The dosages for groups 8, 9, and 10 were 8, 5, and 2.5 ml of La Casera/kg body weight, as well as 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight correspondingly. The results showed that the groups given Tom-Tom and La Casera had lower levels of total protein (TP) and albumin (Alb), and significantly (p < 0.05) higher serum levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), total cholesterol (T-Chol), triacylglycerol (TAG), and low-density lipoprotein cholesterol (LDL–C). Furthermore, there was a substantial (p < 0.05) increase in the serum levels of TP, Alb, and ALT between groups 7 and 5. Prolonged use of Tom-Tom mixed with La Casera should be avoided due to the detrimental alterations in biochemical parameters and subsequent health repercussions.

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Publication Details

Journal
Food systems
Published
2025-04-25
DOI
https://doi.org/10.21323/2618-9771-2025-8-1-106-113
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Biochemical changes in rats after treatment with soft drink and menthol flavoured candy

Dina S. Ahmed, Emad͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Yousif, Ali Basem, Joseph Oghenewogaga Owheruo et al.
Food systems
Alcohol Consumption and Health Effects
article

Biochemical changes in rats after treatment with soft drink and menthol flavoured candy

Dina S. Ahmed, Emad͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Yousif, Ali Basem, Joseph Oghenewogaga Owheruo, Arthur Efeoghene Athan Essaghah, Patrick Othuke Akpoghelie, Huzaifa Umar, Great Iruoghene Edo, Joel Okpoghono, Israel Oghenevwodokohwo Okoro, Edith Omozefe Okoro, Endurance Fegor Isoje, Solomon Ugochukwu Okom
article en

Abstract

The current study looked at the biochemical variations that occurred in rats after they were given menthol flavoured candies and soft drinks. Seventy male Wistar albino rats in total were acquired, split up into ten treatments of seven rats each, and treated with the following regimen for forty-two days. Group 1 is the control. Groups 2, 3, and 4 received 8, 5, and 2.5 ml of La Casera/kg body weight. Groups 5, 6, and 7 received 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight. The dosages for groups 8, 9, and 10 were 8, 5, and 2.5 ml of La Casera/kg body weight, as well as 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight correspondingly. The results showed that the groups given Tom-Tom and La Casera had lower levels of total protein (TP) and albumin (Alb), and significantly (p < 0.05) higher serum levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), total cholesterol (T-Chol), triacylglycerol (TAG), and low-density lipoprotein cholesterol (LDL–C). Furthermore, there was a substantial (p < 0.05) increase in the serum levels of TP, Alb, and ALT between groups 7 and 5. Prolonged use of Tom-Tom mixed with La Casera should be avoided due to the detrimental alterations in biochemical parameters and subsequent health repercussions.

Food systemsVol. 8(1)
University of Science and Technology (YE), Delta State University (NG), College of Medical Sciences (NP), Middle Technical University (IQ), Near East University (CY), Delta State University (US)
Openalex Percentile: Top 88%
Alcohol Consumption and Health Effects
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