G-Protein-coupled Estrogen Receptor 1 (GPER1) Overexpression Affects Aggressiveness of Cervical Carcinoma Cells Depending on Histological Entity
GPER1-OE resulted in a more aggressive tumor behavior of SiHa CSCC cells and a less aggressive tumor behavior of HeLa CAC cells, due to a different effect of GPER1 overexpression depending on the respective histological subtypes of CC. This underlines the need for personalized medicine and a precise differentiation of subtypes in CC-related research.
Authors
- Carsten Gründker (ORCID: https://orcid.org/0000-0001-8828-7955)
- Julia Gallwas (ORCID: https://orcid.org/0000-0001-9640-1973)
- Lothar Hambach (ORCID: https://orcid.org/0000-0001-9734-056X)
Institutions
- Universitätsmedizin Göttingen (DE)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2025-04-25
- DOI
- https://doi.org/10.21873/cgp.20509
- Citations
- 3
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 5.45