Serum Starvation-induced ROS Production Activates the ERK-AP-1-TfR1 Pathway to Up-regulate Survivin to Support Nasopharyngeal Carcinoma Cell Viability
The serum starvation-induced ROS-ERK-AP-1 axis is crucial for the up-regulation of TfR1, which contributes to survivin expression and ultimately sustains the viability of NPC cells.
Authors
- Yingxiao Li
- Tae Hyun Hwang (ORCID: https://orcid.org/0000-0002-6668-7269)
- Ching‐Feng Lien (ORCID: https://orcid.org/0000-0001-8245-5495)
- Chih-Chun Wang
- Yu-Yan Lan (ORCID: https://orcid.org/0000-0003-4436-2057)
Institutions
- E-Da Hospital (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2025-04-25
- DOI
- https://doi.org/10.21873/cgp.20513
- Citations
- 1
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81