KRIBB11 Exerts Anticancer Effects on A172 Glioblastoma Cells<i>via</i>the Cdh1/SKP2/p27 and HSF1/p53/p21 Pathways

KRIBB11 induces apoptotic cell death in A172 cells through two axes: HSF1-dependent p53/p21 accumulation and Cdh1/SKP2-dependent reduction of p27.

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Publication Details

Journal
Cancer Genomics & Proteomics
Published
2025-04-25
DOI
https://doi.org/10.21873/cgp.20514
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00

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KRIBB11 Exerts Anticancer Effects on A172 Glioblastoma Cellsviathe Cdh1/SKP2/p27 and HSF1/p53/p21 Pathways

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article en

Abstract

KRIBB11 induces apoptotic cell death in A172 cells through two axes: HSF1-dependent p53/p21 accumulation and Cdh1/SKP2-dependent reduction of p27.

Cancer Genomics & ProteomicsVol. 22(3)
Catholic University of Korea (KR)
National Research Foundation, Korea Health Industry Development Institute, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Zero hunger
Openalex Percentile: Top 92%
RNA modifications and cancer
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