Measurement of bilirubin in cerebrospinal fluid using the oxidase method on automated chemistry system advia XPT

Quantitative measurement of bilirubin in CSF using the bilirubin oxidase method on the automated Advia XPT platform perform well, with the analysis of low concentrations of bilirubin displaying a high precision and a high concordance with the results of spectrophotometry. These preliminary findings are indicative of the merits of quantitative measurement, that warrants further study of its diagnostic potential as an alternative to the more cumbersome spectrophotometry for diagnosing SAH.

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Publication Details

Journal
Practical Laboratory Medicine
Published
2025-04-25
DOI
https://doi.org/10.1016/j.plabm.2025.e00473
Primary Topic
Hemoglobin structure and function
Type
article
Field-Weighted Citation Impact
0.00

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article

Measurement of bilirubin in cerebrospinal fluid using the oxidase method on automated chemistry system advia XPT

Ida Branzell, Göran Larsson, Dieter Samyn, Paul Pettersson-Pablo
Practical Laboratory Medicine
Hemoglobin structure and function
article

Measurement of bilirubin in cerebrospinal fluid using the oxidase method on automated chemistry system advia XPT

Ida Branzell, Göran Larsson, Dieter Samyn, Paul Pettersson-Pablo
article en

Abstract

Quantitative measurement of bilirubin in CSF using the bilirubin oxidase method on the automated Advia XPT platform perform well, with the analysis of low concentrations of bilirubin displaying a high precision and a high concordance with the results of spectrophotometry. These preliminary findings are indicative of the merits of quantitative measurement, that warrants further study of its diagnostic potential as an alternative to the more cumbersome spectrophotometry for diagnosing SAH.

Practical Laboratory MedicineVol. 45
Örebro University (SE), Örebro University Hospital (SE)
Universitetssjukhuset Örebro
Openalex Percentile: Top 91%
Hemoglobin structure and function
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