NPR is an independent risk factor for predicting all-cause mortality in patients with metabolic dysfunction-associated steatotic liver disease: evidence from NHANES 2007–2020
Neutrophil-associated inflammatory markers are independently associated with MASLD and ALF. Specifically, the ln-transformed NHR and SII show promise as diagnostic markers for MASLD and ALF, respectively. Moreover, elevated ln-transformed NPR is independently associated with an increased risk of all-cause mortality in individuals with MASLD, highlighting the potential clinical relevance of these inflammatory markers in the context of steatotic liver disease.
Authors
- Zhijun Bao (ORCID: https://orcid.org/0000-0002-0900-7204)
- Jiaheng Shi
- Jiaofeng Wang
- Jie Chen (ORCID: https://orcid.org/0000-0002-7503-8236)
- Dan Ye (ORCID: https://orcid.org/0000-0002-5725-8956)
- Xueying Ji
- Yiming Ma
- Xiaona Hu
Institutions
- Huadong Hospital (CN)
- YangPu Geriatric Hospital (CN)
Publication Details
- Journal
- Population Health Metrics
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1186/s12963-025-00378-w
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- National Key Research and Development Program of China