Characterization of the Biochemical Recurrence Prediction Ability and Progression Correlation of Peroxiredoxins Family in Prostate Cancer Based on Integrating Single‐Cell <scp>RNA</scp> ‐Seq and Bulk <scp>RNA</scp> ‐Seq Cohorts
This study offers new evidence for determining that the expression of PRDX5 is associated with advanced tumor grade, poor prognosis, and suboptimal response to multiple therapies in PCa within the PRDXs family. Last but not least, our study provides new insights into precision medicine in PCa and provides a reference for further research on PRDX5.
Authors
- Jinchuang Li
- Weide Zhong (ORCID: https://orcid.org/0000-0002-0430-2845)
- Shanghua Cai
- Shan Tang (ORCID: https://orcid.org/0000-0002-3083-8598)
- Keping Ning
- Chuyang Huang (ORCID: https://orcid.org/0000-0001-5943-7088)
- Yulin Deng (ORCID: https://orcid.org/0009-0001-5286-4703)
- Zeheng Tan
- Jianheng Ye
- Feng Liu (ORCID: https://orcid.org/0009-0003-9694-0602)
- Zhaodong Han
- Huichan He
- Hongwei Luo (ORCID: https://orcid.org/0000-0001-9369-9495)
- Yuanfa Feng
- Wei‐Cheng Tian
- Yongding Wu (ORCID: https://orcid.org/0009-0000-4874-2589)
Institutions
- Guangdong Medical College (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou First People's Hospital (CN)
- Dongguan People’s Hospital (CN)
- The Central Hospital of Shaoyang (CN)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1002/cam4.70855
- Citations
- 1
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Health Commission of Hunan Province
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project