Understanding blood clot mechanical stability: the role of factor XIIIa-mediated fibrin crosslinking in rupture resistance

These findings reveal a significant contribution of fibrin crosslinking to the fracture toughness of fibrin clots, suggesting a role in the propensity for embolization.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2025-04-25
DOI
https://doi.org/10.1016/j.rpth.2025.102871
Citations
10
Primary Topic
Blood properties and coagulation
Type
article
Field-Weighted Citation Impact
15.18
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article

Understanding blood clot mechanical stability: the role of factor XIIIa-mediated fibrin crosslinking in rupture resistance

Ranjini K. Ramanujam, Lauren G. Poole, Valerie J. Tutwiler, J.L. Bassani et al.
10 citations
Research and Practice in Thrombosis and Haemostasis
Blood properties and coagulation
15.18
article

Understanding blood clot mechanical stability: the role of factor XIIIa-mediated fibrin crosslinking in rupture resistance

Ranjini K. Ramanujam, Lauren G. Poole, Valerie J. Tutwiler, J.L. Bassani, Yona Lavi
article en
10 citations

Abstract

These findings reveal a significant contribution of fibrin crosslinking to the fracture toughness of fibrin clots, suggesting a role in the propensity for embolization.

Research and Practice in Thrombosis and HaemostasisVol. 9(4)
Rutgers, The State University of New Jersey (US), Johnson University (US), University of Pennsylvania (US)
Openalex Percentile: Top 1%
Blood properties and coagulation
15.18
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