Untargeted lipidomics profiling provides novel insights into pediatric patients with sepsis: an exploratory study
Alterations in plasma lipid profiles among children with sepsis reflect disease severity, systemic inflammatory responses, and sepsis prognosis. These findings underscore the prognostic potential of lipidomics and its value in understanding sepsis pathophysiology.
Authors
- Caiyan Zhang (ORCID: https://orcid.org/0000-0001-6117-9807)
- Hongyi Zhou (ORCID: https://orcid.org/0000-0001-5074-5180)
- Tingyan Liu (ORCID: https://orcid.org/0000-0001-9188-3694)
- Weili Yang (ORCID: https://orcid.org/0000-0002-2281-6073)
- Guoyun Su
- Guoping Lu
- Kexin Wang (ORCID: https://orcid.org/0000-0003-0124-0631)
- Weiming Chen (ORCID: https://orcid.org/0000-0003-4868-1602)
- Yaodong Wang (ORCID: https://orcid.org/0000-0001-9671-6035)
- Ye Cheng (ORCID: https://orcid.org/0000-0003-2340-7228)
- Hehe Chen
- Jiayi Bai
- Zimei Cheng (ORCID: https://orcid.org/0000-0002-3994-8339)
- Ying Liu (ORCID: https://orcid.org/0000-0002-7164-962X)
- Reyihangu Awuti
Institutions
- Fudan University (CN)
- Ministry of Science and Technology (LA)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1007/s11306-025-02255-x
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China
- Natural Science Foundation of Anhui Province
- National Key Research and Development Program of China