Safety of ifosfamide during pregnancy: A comprehensive analysis
Altogether, this comprehensive analysis supports that ifosfamide may induce fetal nephrotoxicity in pregnant women. It can result in intrauterine growth restriction, oligohydramnios and neonatal acute renal failure, as well as fetal death especially for early exposure during the first half of pregnancy.
Authors
- Marine Auffret (ORCID: https://orcid.org/0000-0002-5236-9083)
- Vassilis Tsatsaris (ORCID: https://orcid.org/0000-0002-7650-6660)
- Laurent Chouchana (ORCID: https://orcid.org/0000-0002-9626-3571)
- Laurence Lagarce (ORCID: https://orcid.org/0000-0002-7609-6972)
- Tessa Pietri (ORCID: https://orcid.org/0009-0004-6466-7776)
- Jean‐Marc Tréluyer (ORCID: https://orcid.org/0000-0002-2045-4742)
- Charlotte Devant (ORCID: https://orcid.org/0009-0005-5274-1294)
- Mathilde Barrois
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Aix-Marseille Université (FR)
- Assistance Publique Hôpitaux de Marseille (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Maternité Port Royal (FR)
- Hospices Civils de Lyon (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
Publication Details
- Journal
- European Journal of Obstetrics & Gynecology and Reproductive Biology
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1016/j.ejogrb.2025.114003
- Citations
- 2
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.09