Comparison of left atrial appendage closure and oral anti-coagulation after catheter ablation for atrial fibrillation: Concomitant and sequential cohorts of the OPTION randomized controlled trial
For both Concomitant and Sequential ablation timing strategies, LAAC has similar efficacy compared with OAC and a lower risk of clinically important post-procedure bleeding in high-risk patients following AF ablation.
Authors
- Bradley P. Sutton (ORCID: https://orcid.org/0000-0002-8443-0408)
- Walid Saliba
- Marek Grygier (ORCID: https://orcid.org/0000-0002-1134-7099)
- Moussa Mansour (ORCID: https://orcid.org/0009-0001-7890-2122)
- Thomas Christen (ORCID: https://orcid.org/0000-0002-0820-410X)
- Devi Nair
- Brian Schuler
- Nazmul Islam
- Vivek Y. Reddy (ORCID: https://orcid.org/0000-0002-5638-4993)
- Oussama M. Wazni (ORCID: https://orcid.org/0000-0001-7115-7716)
- Andrea Natale (ORCID: https://orcid.org/0000-0002-5487-0728)
- Kasey J. Leger (ORCID: https://orcid.org/0000-0002-7905-6714)
- Vijendra Swarup
- Stanislav Weiner
- Manish A. Shah (ORCID: https://orcid.org/0000-0002-6913-9655)
- José Luis Ibáñez (ORCID: https://orcid.org/0000-0003-0792-6669)
- Vivek Iyer (ORCID: https://orcid.org/0000-0003-4451-8293)
- T. A. Hall
- Guillaume Duthoit (ORCID: https://orcid.org/0000-0002-5730-6946)
- Germán Calle Pérez
- Yeruva Madhu Reddy
- Kenneth M. Steín
Institutions
- Poznan University of Medical Sciences (PL)
- MedStar Washington Hospital Center (US)
- York Hospital (GB)
- Cleveland Clinic (US)
- Queen Elizabeth II Jubilee Hospital (AU)
- York General Hospital (US)
- The University of Kansas Health System (US)
- Queensland Rail (AU)
- Boston Scientific (United States) (US)
- Sorbonne Université (FR)
- Massachusetts General Hospital (US)
- Trinity Mother Frances Hospitals and Clinics (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Mount Sinai Hospital (US)
- Mount Sinai Hospital (US)
- Pitié-Salpêtrière Hospital (FR)
- The Arrhythmia Institute (US)
- Hospital General Universitario de Alicante Doctor Balmis (ES)
- Hospital Universitario Puerta del Mar (ES)
- Texas Cardiac Arrhythmia (US)
- St. Joseph Medical Center (US)
- St. Bernards Clopton Clinic (US)
- Marin Endocrine Care and Research (US)
Publication Details
- Journal
- Heart Rhythm
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1016/j.hrthm.2025.04.029
- Citations
- 8
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 11.11
Funders
- Pfizer
- Cleveland Clinic
- Cleveland Clinic Foundation
- Boston Scientific Corporation
- Impulse Dynamics
- Novo Nordisk
- Biosense Webster