Vertebral Artery Microcalcification Detected by 18F-NaF PET/CT

Intracranial atherosclerosis is a leading cause of stroke and cognitive dysfunction. Calcification of intracranial atherosclerotic plaques is commonly observed on noncontrast CT, yet structural imaging alone cannot visualize active microcalcifications characteristic of progressive atheroma. 18 F-NaF is an emerging PET radiotracer of vascular microcalcification that may enable the detection of such pathophysiology. In this report, we present molecular microcalcification of the left vertebral artery incidentally found on 18 F-NaF PET/CT of a 64-year-old man with risk factors for intracranial atherosclerosis.

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Journal
Clinical Nuclear Medicine
Published
2025-04-24
DOI
https://doi.org/10.1097/rlu.0000000000005831
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
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article

Vertebral Artery Microcalcification Detected by 18F-NaF PET/CT

Nirmal Patel, Eric M. Teichner, Thomas Werner, Shiv Patil et al.
Clinical Nuclear Medicine
Cerebrovascular and Carotid Artery Diseases
article

Vertebral Artery Microcalcification Detected by 18F-NaF PET/CT

Nirmal Patel, Eric M. Teichner, Thomas Werner, Shiv Patil, Abass Alavi, Poul Flemming Høilund-Carlsen
article en

Abstract

Intracranial atherosclerosis is a leading cause of stroke and cognitive dysfunction. Calcification of intracranial atherosclerotic plaques is commonly observed on noncontrast CT, yet structural imaging alone cannot visualize active microcalcifications characteristic of progressive atheroma. 18 F-NaF is an emerging PET radiotracer of vascular microcalcification that may enable the detection of such pathophysiology. In this report, we present molecular microcalcification of the left vertebral artery incidentally found on 18 F-NaF PET/CT of a 64-year-old man with risk factors for intracranial atherosclerosis.

Clinical Nuclear MedicineVol. 51(1)
Thomas Jefferson University (US), Odense University Hospital (DK), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 87%
Cerebrovascular and Carotid Artery Diseases
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