Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring
This study established a comprehensive AH proteomic signature of DR progression, offering insights into the pathogenesis of DR and highlighting potential biomarkers and novel therapeutic targets.
Authors
- Junbin Liu (ORCID: https://orcid.org/0000-0001-6521-4227)
- Haoxian Zhu
- Yuanchu Jin
- Xi‐Yu Wu (ORCID: https://orcid.org/0000-0002-4264-8388)
- M. H. Liu (ORCID: https://orcid.org/0000-0001-5490-7757)
- Zhifan Chen
- Xiaoyang Luo
- Liang Zhang (ORCID: https://orcid.org/0000-0003-0782-0688)
- Xinyu Chen (ORCID: https://orcid.org/0000-0002-2132-2186)
- Xueli Zhang (ORCID: https://orcid.org/0000-0001-5963-9261)
- Xiang Fang (ORCID: https://orcid.org/0000-0002-5995-0874)
- Shixiu Liao (ORCID: https://orcid.org/0000-0002-7173-7654)
- Qianli Meng (ORCID: https://orcid.org/0000-0003-0979-5359)
- Ying Cui (ORCID: https://orcid.org/0000-0003-4390-8206)
- Guanrong Wu
Institutions
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Key Laboratory of Guangdong Province (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- South China University of Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1186/s12967-025-06452-z
- Citations
- 3
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.12
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province