Room Temperature Access to Bridged Nitrogen Ligands via Electroreductive Annulation of 1,10-Phenanthrolines and Imines
An electroreductive annulation reaction of 1,10-phenanthrolines and imines has been developed. This method proceeds with broad substrate and functionality tolerance, high selectivity, and no need for pressurized H<sub>2</sub> gas or transition metal catalysts. Mechanistic studies reveal that the products are formed via simultaneous electroreduction of both proton-activated reactants followed by radical cross-coupling and intramolecular cyclization of the coupling adduct.
Authors
- Chengqian Zhang (ORCID: https://orcid.org/0000-0001-7829-0587)
- Maorui Wang (ORCID: https://orcid.org/0009-0009-8159-9804)
- Min Zhang (ORCID: https://orcid.org/0000-0002-7023-8781)
Institutions
- Guangxi Normal University (CN)
- Key Laboratory of Guangdong Province (CN)
- Pulp and Paper Research Institute (SK)
- State Key Laboratory of Pulp and Paper Engineering
- South China University of Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1021/acs.orglett.5c01140
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province