Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia Through Mendelian Randomization and Single-cell RNA Sequencing

These observations emphasize consistent expression patterns among different prostate cell types and suggest a highly interconnected regulatory network that underpins BPH pathology, thereby providing fresh perspectives on the molecular mechanisms underlying the disease.

Authors

Jiahao Liu (ORCID: https://orcid.org/0000-0001-6239-1973)
Yichuan Wang (ORCID: https://orcid.org/0000-0003-1575-0245)
Wei Xiong (ORCID: https://orcid.org/0000-0002-3017-9895)
Long Wang (ORCID: https://orcid.org/0000-0003-4583-2428)
Qing Zhou
Liang Zhou (ORCID: https://orcid.org/0000-0003-4369-5001)

Institutions

Central South University (CN)
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Third Xiangya Hospital (CN)

Publication Details

Journal: The Journals of Gerontology Series A
Published: 2025-04-23
DOI: https://doi.org/10.1093/gerona/glaf073
Citations: 1
Primary Topic: Prostate Cancer Diagnosis and Treatment
Type: article
Field-Weighted Citation Impact: 1.52

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article

Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia Through Mendelian Randomization and Single-cell RNA Sequencing

Jiahao Liu, Yichuan Wang, Wei Xiong, Long Wang et al.

Apr 23, 2025

1 citations

The Journals of Gerontology Series A

Prostate Cancer Diagnosis and Treatment

1.52

article

Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia Through Mendelian Randomization and Single-cell RNA Sequencing

Jiahao Liu, Yichuan Wang, Wei Xiong, Long Wang, Qing Zhou, Liang Zhou

April 23, 2025article en

1 citations

Abstract

These observations emphasize consistent expression patterns among different prostate cell types and suggest a highly interconnected regulatory network that underpins BPH pathology, thereby providing fresh perspectives on the molecular mechanisms underlying the disease.

The Journals of Gerontology Series AVol. 80(7)

Central South University (CN), First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN), Third Xiangya Hospital (CN)

Good health and well-being

Openalex Percentile: Top 19%

Prostate Cancer Diagnosis and Treatment

1.52

DOI Source OpenAlex

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Elucidating Cellular Senescence-related Genes in Benign Prostatic Hyperplasia Through Mendelian Randomization and Single-cell RNA Sequencing — Jiahao Liu, Yichuan Wang, et al. · The Journals of Gerontology Series A (2025) | TGRS Research Map | TGRS