Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black

These findings provide insights into the mechanisms of lung overload and inflammation in rats, and highlight similarities and differences in transcriptomic responses of rat and human alveolar macrophages.

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Publication Details

Journal
Particle and Fibre Toxicology
Published
2025-04-25
DOI
https://doi.org/10.1186/s12989-025-00624-x
Citations
4
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
3.37

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article

Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black

Bertrand Bearzatto, Yousof Yakoub, Antoine Froidure, Caroline Bouzin et al.
4 citations
Particle and Fibre Toxicology
Neuroinflammation and Neurodegeneration Mechanisms
3.37
article

Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black

Bertrand Bearzatto, Yousof Yakoub, Antoine Froidure, Caroline Bouzin, Cristina Pavan, Charles Pilette, Dominique Lison, François Huaux, Laeticia Perez, Jérôme Ambroise, Mihaly Palmai‐Pallag, Laurence Ryelandt
article en
4 citations

Abstract

These findings provide insights into the mechanisms of lung overload and inflammation in rats, and highlight similarities and differences in transcriptomic responses of rat and human alveolar macrophages.

Particle and Fibre ToxicologyVol. 22(1)
Cliniques Universitaires Saint-Luc (BE), University of Turin (IT), UCLouvain (BE)
Université Catholique de Louvain
Openalex Percentile: Top 8%
Neuroinflammation and Neurodegeneration Mechanisms
3.37
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Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black — Bertrand Bearzatto, Yousof Yakoub, et al. · Particle and Fibre Toxicology (2025) | TGRS Research Map | TGRS