Clinical outcomes and management of <i>CDKN2A/B</i> homozygously deleted IDH-mutant astrocytomas—a cohort study and patterns of care survey
This exploratory study supports the importance of molecular profiling in glioma diagnoses and the prognostic utility of current classification systems. However future research into the optimal therapy for these patients is needed in prospective studies.
Authors
- Isabella Wilson (ORCID: https://orcid.org/0009-0008-9735-1320)
- Hao‐Wen Sim (ORCID: https://orcid.org/0000-0002-2530-0523)
- Joe Wei (ORCID: https://orcid.org/0000-0003-1944-1079)
- Angela Bayly
- Michael Krasovitsky (ORCID: https://orcid.org/0000-0001-6287-3593)
- Laveniya Satgunaseelan (ORCID: https://orcid.org/0000-0002-7435-0834)
- David Lok Hang Chan (ORCID: https://orcid.org/0000-0002-7773-3144)
- Cassie Turner
- Benjamin Y. Kong (ORCID: https://orcid.org/0000-0001-8659-5591)
- Amanda L. Hudson (ORCID: https://orcid.org/0000-0002-8275-0395)
- Michael Back (ORCID: https://orcid.org/0000-0003-2363-8333)
- Subotheni Thavaneswaran (ORCID: https://orcid.org/0000-0002-8946-6709)
- Michael E. Buckland (ORCID: https://orcid.org/0000-0003-4755-6471)
- Marina Kastelan (ORCID: https://orcid.org/0000-0003-4866-4124)
- Alexander Yuile (ORCID: https://orcid.org/0000-0002-7242-0528)
- Helen Wheeler (ORCID: https://orcid.org/0000-0002-6949-354X)
- Samuel Miller (ORCID: https://orcid.org/0000-0002-6013-5471)
- Heng Wei (ORCID: https://orcid.org/0000-0003-2944-031X)
- Kimberley L. Alexander (ORCID: https://orcid.org/0000-0002-7239-039X)
- Adrian Y. S. Lee (ORCID: https://orcid.org/0000-0002-5179-4803)
- Winny Varikatt
- Mark Wong
- Zarnie Lwin (ORCID: https://orcid.org/0009-0006-5009-4895)
- Nick Pavlakis
- Maggie Lee
Institutions
- The University of Sydney (AU)
- Garvan Institute of Medical Research (AU)
- The University of Queensland (AU)
- Royal Brisbane and Women's Hospital (AU)
- Royal Prince Alfred Hospital (AU)
- Royal North Shore Hospital (AU)
- Westmead Hospital (AU)
- UNSW Sydney (AU)
- St Vincent's Hospital Sydney (AU)
- Chris O’Brien Lifehouse (AU)
- St Vincent's Clinic (AU)
- The Kinghorn Cancer Centre (AU)
Publication Details
- Journal
- Neuro-Oncology Practice
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1093/nop/npaf045
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.25
Funders
- Amgen
- Pfizer
- Gilead Sciences
- BeiGene