Hormonal influence on adenomatoid odontogenic tumor: A case report in pregnancy

Introduction: Pregnancy is a delicate physiologic state accompanied by increased risk of pathologic exposure. Oral complications like gingival enlargements, epulis, etc. are commonly seen in pregnant women owing to immune and hormonal changes. Although very few cases of odontogenic tumors have been reported, many authors have reported major estrogen-dependent tumors presumed to arise due to differences in genetic expression. Similarly, the influence of hormones in the growth of odontogenic tumors is also postulated. The correlation of certain proteins and receptors is being reviewed to understand the pathophysiology of potential interactions between hormones and odontogenic tumor cells. The literature search was conducted with the aim to derive a vivid explanation by identifying a common component between pregnancy and the occurrence of head and neck tumors. Case Report: A report of patient in third trimester of pregnancy presenting with an odontogenic tumor, followed by a review of the possible relation between hormone and occurrence of odontogenic tumors in pregnant women. Conclusion: Understanding the relationship between hormonal levels in females and the occurrence of jaw tumors will emphasize on importance of screening and follow-up of oral cavity in pregnant population and appropriate referral to a specialist, if necessary.