Incorrect blood typing and mis‐transfusion due to low‐titer group O whole blood resuscitation
Our findings highlight a rare but clinically significant risk of ABO typing errors following LTOWB transfusion, primarily due to contamination of patient samples with donor blood. Such errors carry the potential for acute hemolytic reactions, underscoring the critical need for strict adherence to sampling protocols. Whenever possible, ABO typing should be performed prior to LTOWB administration, and samples should be drawn from a site contralateral to the transfusion.
Authors
- Jessica Schucht
- Jeremy W. Jacobs (ORCID: https://orcid.org/0000-0002-5719-9685)
- Jill R. Streams
- Miriam Brown (ORCID: https://orcid.org/0000-0001-5006-7068)
- Garrett S. Booth (ORCID: https://orcid.org/0000-0002-8422-9480)
- Christine Schaeffer‐Reiss (ORCID: https://orcid.org/0000-0003-0672-1979)
- Kaycie Atchison (ORCID: https://orcid.org/0000-0002-8948-9396)
- Toufik Tahiri
- Bradley M. Dennis (ORCID: https://orcid.org/0000-0002-2419-2102)
- Deva Sharma (ORCID: https://orcid.org/0000-0002-6437-5296)
- Elisha Hall (ORCID: https://orcid.org/0000-0001-9156-7253)
- A. MUELLER
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1111/trf.18268
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00