Development of commutable candidate certified reference materials from protein solutions: concept and application to human insulin

A new concept for developing commutable RMs with pure protein material, which avoids the challenges in developing commutable matrix RMs and should contribute to the standardization of clinical test results for proteins, was successfully applied to develop commutable hINS solution cCRMs.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2025-04-24
DOI
https://doi.org/10.1515/cclm-2025-0329
Primary Topic
Protein purification and stability
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of commutable candidate certified reference materials from protein solutions: concept and application to human insulin

Shiwen Luo, Yao Tan, Yahui Liu, Jing Wang et al.
Clinical Chemistry and Laboratory Medicine (CCLM)
Protein purification and stability
article

Development of commutable candidate certified reference materials from protein solutions: concept and application to human insulin

Shiwen Luo, Yao Tan, Yahui Liu, Jing Wang, Ziliang Wang, Liqing Wu, Bin Yang
article en

Abstract

A new concept for developing commutable RMs with pure protein material, which avoids the challenges in developing commutable matrix RMs and should contribute to the standardization of clinical test results for proteins, was successfully applied to develop commutable hINS solution cCRMs.

Clinical Chemistry and Laboratory Medicine (CCLM)Vol. 63(9)
National Institute of Metrology (CN)
Industry, innovation and infrastructure
Openalex Percentile: Top 92%
Protein purification and stability
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