Eosinophils but not mast cells exert anti-tumorigenic activity, without being predictive markers of the long-term response to Bacillus Calmette-Guérin (BCG) therapy in patients with bladder carcinoma
Even though eosinophils exhibit anti-tumorigenic effects in bladder cancer, neither MCs nor eosinophils were predictive of the long-term BCG therapy response. However, our findings implicate that matrix-related factors may modulate BCG therapy responses.
Authors
- Ilan Zaffran
- Yara Zoabi
- Fidan Rahimli Alekberli
- Vladimir Yutkin (ORCID: https://orcid.org/0000-0002-9404-4025)
- Ekaterini Tiligada (ORCID: https://orcid.org/0000-0002-4620-8398)
- Francesca Levi‐Schaffer (ORCID: https://orcid.org/0000-0003-0620-2810)
- Pratibha Gaur (ORCID: https://orcid.org/0000-0002-3155-5944)
Institutions
- Hebrew University of Jerusalem (IL)
- National and Kapodistrian University of Athens (GR)
- Hadassah Medical Center (IL)
Publication Details
- Journal
- Inflammation Research
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1007/s00011-025-02028-1
- Citations
- 1
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Hadassah Medical Organization
- Hebrew University of Jerusalem
- Israeli Centers for Research Excellence