Estimation of therapeutic threshold for tuberculosis using adapted nominal group technique and clinical vignettes in clinical and community settings in Southern Africa
The aNGT produced a reliable estimate of ThT. The difference in the estimates of ThT between the aNGT and CVs may have a limited impact on clinical decisions. Factors influencing ThT and the acceptability of results by healthcare workers will be explored in focus group discussions and in-depth interviews.
Authors
- Alastair van Heerden (ORCID: https://orcid.org/0000-0003-2530-6885)
- Tom Decroo (ORCID: https://orcid.org/0000-0002-1205-1484)
- Tom Boyles (ORCID: https://orcid.org/0000-0002-5676-8081)
- Lutgarde Lynen (ORCID: https://orcid.org/0000-0001-7183-4895)
- Carlos Kiyan
- Irene Ayakaka (ORCID: https://orcid.org/0000-0003-1051-5684)
- Shannon Bosman
- Lindani Msimango (ORCID: https://orcid.org/0000-0002-0009-0187)
- Mashaete Kamele
- Alfred Keter (ORCID: https://orcid.org/0000-0003-2141-4838)
- Bart K. M. Jacobs (ORCID: https://orcid.org/0000-0002-4677-0911)
- Klaus Reither (ORCID: https://orcid.org/0000-0001-6195-8237)
- Thandanani Madonsela (ORCID: https://orcid.org/0009-0005-8473-622X)
- Lenika Naiken (ORCID: https://orcid.org/0009-0009-8337-0376)
Institutions
- Human Sciences Research Council (ZA)
- South African Medical Research Council (ZA)
- University of London (GB)
- HOGENT University of Applied Sciences and Arts (BE)
- Swiss Tropical and Public Health Institute (CH)
- National University of Lesotho (LS)
- University of Basel (CH)
- University of the Witwatersrand (ZA)
- Ghent University (BE)
- London School of Hygiene & Tropical Medicine (GB)
- Aga Khan University Nairobi (KE)
- Helen Joseph Hospital (ZA)
- Right to Care (ZA)
- Instituut voor Tropische Geneeskunde (BE)
Publication Details
- Journal
- Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1016/j.jctube.2025.100529
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- European Commission
- European and Developing Countries Clinical Trials Partnership