Insights into the molecular mechanism of pulmonary vein stenosis in pediatric patients with congenital heart disease
These results suggests that aggressive PPVS phenotype may be driven by an increase in <i>PIEZO1</i> expression and subsequent changes in extracellular matrix production. The clinical and therapeutic relevance of <i>PIEZO1</i> warrant further investigation.
Authors
- Pengfei Ji (ORCID: https://orcid.org/0009-0002-0451-3009)
- Lalita Wadhwa (ORCID: https://orcid.org/0000-0003-4506-7826)
- Alyssa B. Kalustian (ORCID: https://orcid.org/0000-0001-9971-6444)
- Ravi K. Birla
- Athar M. Qureshi (ORCID: https://orcid.org/0000-0001-5992-568X)
- Manish Bansal (ORCID: https://orcid.org/0000-0001-9223-5795)
- Christopher A. Caldarone
- Jeffrey S. Heinle
Institutions
- Adult Congenital Heart Association (US)
- Texas Children's Hospital (US)
- Baylor Jack and Jane Hamilton Heart and Vascular Hospital (US)
Publication Details
- Journal
- JTCVS Open
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1016/j.xjon.2025.04.012
- Citations
- 1
- Primary Topic
- Erythrocyte Function and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 1.16