Clinicopathological characteristics of transcription factor-defined subtypes in bladder small cell carcinoma

NEUROD1 is characteristically expressed in bladder SmCC, especially in SmCC combined with UC, suggesting a distinct phenotype from prostate SmCC. These findings highlight the potential for TF-based classification to improve diagnostic accuracy and inform therapeutic strategies.

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Publication Details

Journal
BMC Cancer
Published
2025-04-24
DOI
https://doi.org/10.1186/s12885-025-14157-1
Primary Topic
Lung Cancer Research Studies
Type
article
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article

Clinicopathological characteristics of transcription factor-defined subtypes in bladder small cell carcinoma

Kentaro Inamura, Keiichiro Kitahama, Kengo Takeuchi, Rumiko Saito et al.
1 links
BMC Cancer
Lung Cancer Research Studies
article

Clinicopathological characteristics of transcription factor-defined subtypes in bladder small cell carcinoma

Kentaro Inamura, Keiichiro Kitahama, Kengo Takeuchi, Rumiko Saito, Akihiro Ohmoto, Yasuyuki Shigematsu, Junji Yonese, Gulanbar Amori, Emiko Sugawara, Mahmut Amori
article en

Abstract

NEUROD1 is characteristically expressed in bladder SmCC, especially in SmCC combined with UC, suggesting a distinct phenotype from prostate SmCC. These findings highlight the potential for TF-based classification to improve diagnostic accuracy and inform therapeutic strategies.

BMC CancerVol. 25(1)
Jichi Medical University (JP), Kyorin University (JP), The Cancer Institute Hospital (JP), Japan Society of Chemotherapy (JP), Japanese Foundation For Cancer Research (JP), Chiba Institute of Technology (JP)
Openalex Percentile: Top 87%
Lung Cancer Research Studies
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