Exploring the Impact of Backward and Forward Locomotor Treadmill Training in Chronic Stroke Survivors with Severe Post-Stroke Walking Impairment: A Single-Center Pilot Randomized Controlled Trial
While preliminary, this study found that 12 training sessions did not lead to group-level achievement of MCID for walking speed in our cohort and found no significant between-group differences in walking capacity or dynamic postural stability. Future well-powered dosing trials and mechanistically driven studies are needed to optimize and identify predictors of training response.
Authors
- Kari Dunning (ORCID: https://orcid.org/0000-0002-0705-7734)
- Pierce Boyne (ORCID: https://orcid.org/0000-0003-3611-9057)
- Tamiel Murray
- Heidi Sucharew (ORCID: https://orcid.org/0000-0002-3933-1574)
- S. Appala Naidu
- Colin Drury (ORCID: https://orcid.org/0000-0002-0999-3905)
- Oluwole O. Awosika (ORCID: https://orcid.org/0000-0002-5286-931X)
- Eduardo Palermo (ORCID: https://orcid.org/0000-0002-3213-8261)
- Changchun Xie (ORCID: https://orcid.org/0000-0002-1843-4099)
- Khwahish Singh
Institutions
- Wright State University (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-04-24
- DOI
- https://doi.org/10.3390/brainsci15050437
- Citations
- 1
- Primary Topic
- Stroke Rehabilitation and Recovery
- Type
- article
- Field-Weighted Citation Impact
- 1.03