Nanoscale Formulations for Targeted Drug Delivery: Enhancing Stability, Release Control and Therapeutic Efficacy
The present study focuses on the nanoscale formulation technique for pharmacological agent delivery, avoiding the shortcomings of conventional protocols, such as rapid pharmaceutical clearance, limited site-specific accuracy and reduced biological accessibility. The goal of this is that because nanoscale particles can improve stability, control pharmaceutical release and increase penetration, they have emerged as a promising drug delivery technology. Targeted therapies for conditions like septicemia and bronchial asthma can be developed by attaching particular molecular binders to nanoscale particles. This reduces toxicity while maximizing therapeutic efficacy. In summary, this analysis highlights the medicinal delivery potential of nanoscale formulations, including the mechanisms of action of botanical constituents such as flavonoids and triterpenoidal compounds. It also implies that the administration of inflammatory conditions may benefit greatly from the use of nanoscale particles loaded with these compounds.
Authors
- J Pavan Kumar
- Ramaiyan Velmurugan (ORCID: https://orcid.org/0000-0002-9399-3579)
- Lokeshvar Ravikumar (ORCID: https://orcid.org/0000-0001-6869-3446)
- Patibandla Jahnavi
- Pradeep Vidiyala
- Rahul A Rahul
- Bhuvaneshwaran P Bhuvaneshwaran
Institutions
- Siddhartha Medical College (IN)
- Raffles University Iskandar (MY)
- Elixir Medical (United States) (US)
- Saveetha University (IN)
Publication Details
- Journal
- International Journal of Pharmaceutical Investigation
- Published
- 2025-04-23
- DOI
- https://doi.org/10.5530/ijpi.20250189
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00