Synthesis and Spectral Analysis of Novel Substituted Benzimidazole Derivatives

Aim The aim of the present study is to synthesize novel series of substituted benzimidazole derivatives and their spectral characterization.Materials and Methods This study presents research on the synthesis of novel series of substituted benzimidazole derivatives using primary amine as the starting compound.Results All synthesized compounds were analyzed using 1 hydrogen nuclear magnetic resonance, Fourier transform infrared and mass spectrometry to validate their structures.Conclusion Overall, the exploration of substituted benzimidazole derivatives with varied functional groups as potential candidates for further advancement as therapeutic agents.

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Publication Details

Journal
International Journal of Pharmaceutical Investigation
Published
2025-04-23
DOI
https://doi.org/10.5530/ijpi.20250160
Primary Topic
Synthesis and biological activity
Type
article
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article

Synthesis and Spectral Analysis of Novel Substituted Benzimidazole Derivatives

B. L. Jadhav, Sushil P. Narkhede
International Journal of Pharmaceutical Investigation
Synthesis and biological activity
article

Synthesis and Spectral Analysis of Novel Substituted Benzimidazole Derivatives

B. L. Jadhav, Sushil P. Narkhede
article en

Abstract

Aim The aim of the present study is to synthesize novel series of substituted benzimidazole derivatives and their spectral characterization.Materials and Methods This study presents research on the synthesis of novel series of substituted benzimidazole derivatives using primary amine as the starting compound.Results All synthesized compounds were analyzed using 1 hydrogen nuclear magnetic resonance, Fourier transform infrared and mass spectrometry to validate their structures.Conclusion Overall, the exploration of substituted benzimidazole derivatives with varied functional groups as potential candidates for further advancement as therapeutic agents.

International Journal of Pharmaceutical InvestigationVol. 15(3)
Sandip Foundation (IN), Pharmaceutical Biotechnology (Czechia) (CZ)
Openalex Percentile: Top 93%
Synthesis and biological activity
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