Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective

In today’s modern world, there is a rapid increase in the control and systemic administration of drugs through the oral route, because of its various advantages like high patient compliance, easy dose administration and availability of various formulations. One of the novel approaches in this area is Gastro Retentive Drug Delivery Systems (GRDDs) is a systemic approach to increase the gastric residence time of the drug which results in the site-specific drug release of drug in the upper part of GIT for local and systemic effect of the drug. It is a unique approach that has become more popular in the last three decades. The sole purpose of this article is to summarize and present recent as well as past article which focuses on the GRDDs and their various aspects. This article addresses briefly on various aspects of GRDDs their classification, advantages and limitations, factors affecting gastric residence time, evaluation, recent advancements, regulatory requirements and future prospective of GRDDs.

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Publication Details

Journal
International Journal of Pharmaceutical Investigation
Published
2025-04-23
DOI
https://doi.org/10.5530/ijpi.20250244
Citations
3
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
2.37
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article

Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective

Deshraj Chumbhale, Pijush Dutta, Priyanka Shukla, Ruchi Tiwari et al.
3 citations
International Journal of Pharmaceutical Investigation
Drug Solubulity and Delivery Systems
2.37
article

Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective

Deshraj Chumbhale, Pijush Dutta, Priyanka Shukla, Ruchi Tiwari, Saket Mishra, Dhakshnamoorthy Vellingiri
article en
3 citations

Abstract

In today’s modern world, there is a rapid increase in the control and systemic administration of drugs through the oral route, because of its various advantages like high patient compliance, easy dose administration and availability of various formulations. One of the novel approaches in this area is Gastro Retentive Drug Delivery Systems (GRDDs) is a systemic approach to increase the gastric residence time of the drug which results in the site-specific drug release of drug in the upper part of GIT for local and systemic effect of the drug. It is a unique approach that has become more popular in the last three decades. The sole purpose of this article is to summarize and present recent as well as past article which focuses on the GRDDs and their various aspects. This article addresses briefly on various aspects of GRDDs their classification, advantages and limitations, factors affecting gastric residence time, evaluation, recent advancements, regulatory requirements and future prospective of GRDDs.

International Journal of Pharmaceutical InvestigationVol. 15(3)
University of Iowa (US), University of Engineering & Management (IN), Hindu College of Pharmacy (IN)
Good health and well-being
Openalex Percentile: Top 12%
Drug Solubulity and Delivery Systems
2.37
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Exploring the Potential of Gastro Retentive Drug Delivery Systems: An Insightful Perspective — Deshraj Chumbhale, Pijush Dutta, et al. · International Journal of Pharmaceutical Investigation (2025) | TGRS Research Map | TGRS