Diagnostic Accuracy of Finger-Like Projections and Subarachnoid Hemorrhage for Cerebral Amyloid Angiopathy: Pathological Validation From Lobar Hematoma Evacuation or Brain Biopsy
This study is the first to evaluate the diagnostic performance of FLP and SAH with histopathologic reference in nonautopsied patients. The results suggest these markers have lower diagnostic performance than previously reported in severe hematomas leading to early death. However, the high sensitivity of SAH suggests its potential clinical utility in ruling out CAA when absent.
Authors
- Hassan Hosseini (ORCID: https://orcid.org/0000-0002-2169-3788)
- Andreas Charidimou (ORCID: https://orcid.org/0000-0001-5891-337X)
- Peggy Reiner
- Catherine Oppenheim (ORCID: https://orcid.org/0000-0003-3410-0862)
- Homa Adle‐Biassette (ORCID: https://orcid.org/0000-0001-9446-8306)
- Virginie Desestret (ORCID: https://orcid.org/0000-0001-9643-1558)
- Marine Le Corre
- Pierre Seners (ORCID: https://orcid.org/0000-0002-2134-0691)
- David Meyronet (ORCID: https://orcid.org/0000-0001-9943-4578)
- Jean‐Claude Baron (ORCID: https://orcid.org/0000-0002-5264-2588)
- Joseph Benzakoun (ORCID: https://orcid.org/0000-0002-0733-0104)
- Julien Savatovsky (ORCID: https://orcid.org/0000-0002-6732-1779)
- Michaël Obadia (ORCID: https://orcid.org/0000-0001-6777-6311)
- Alexandre Bani‐Sadr (ORCID: https://orcid.org/0000-0002-1808-2484)
- Guillaume Turc (ORCID: https://orcid.org/0000-0001-5059-4095)
- Norbert Nighoghossian (ORCID: https://orcid.org/0000-0003-0594-4409)
- Sébastien Froelich (ORCID: https://orcid.org/0000-0001-9124-2395)
- Valérie Rigau (ORCID: https://orcid.org/0000-0002-8017-5489)
- Adrien ter Schiphorst (ORCID: https://orcid.org/0000-0002-7354-3351)
- Caroline Le Guérinel (ORCID: https://orcid.org/0000-0002-2101-1804)
- Marc‐Antoine Labeyrie (ORCID: https://orcid.org/0000-0002-3224-7994)
- Johan Pallud (ORCID: https://orcid.org/0000-0002-1652-9844)
- Pascale Varlet (ORCID: https://orcid.org/0000-0002-8164-1517)
- Alexandra Maury (ORCID: https://orcid.org/0009-0004-6436-9074)
- David Calvet
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Boston University (US)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Lyon College (US)
- Université Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Hôpital Gui de Chauliac (FR)
- Hôpital Lariboisière (FR)
- Fondation de Rothschild (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- FHU Neurovasc (FR)
- Institut Mondor de Recherche Biomédicale (FR)
Publication Details
- Journal
- Stroke
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1161/strokeaha.124.050159
- Citations
- 3
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 4.17