Upregulated Lactate Dehydrogenase C4 Promotes Hepatocellular Carcinoma Progression Via Accelerating Glycolysis and Triggering the AKT/mTOR Signaling Pathway
Lactate dehydrogenase C4 (LDHC4) plays a crucial role in regulating the interconversion between lactate and pyruvate during glucose metabolism. Yet, its expression patterns and biological roles in hepatocellular carcinoma (HCC) remain largely unknown. This study endeavors to elucidate the expression and biological function of LDHC4 in HCC.
Authors
- Xiao Zhang (ORCID: https://orcid.org/0000-0003-2547-7262)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Biomedical Journal of Scientific & Technical Research
- Published
- 2025-03-19
- DOI
- https://doi.org/10.26717/bjstr.2025.61.009541
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00