The use of bisphosphonate and testosterone in young people with Duchenne muscular dystrophy: an international clinician survey
This international survey highlights variability in the management of osteoporosis and delayed puberty in DMD. Recommendations on management of side-effects of IV bisphosphonate, osteoporosis therapy during transition, and longer-term treatment into adulthood is required. There is a need for further guidance on testosterone therapy, particularly in regard to monitoring after discontinuation and the threshold for re-initiation of treatment.
Authors
- Sarah McCarrison
- Justin H. Davies (ORCID: https://orcid.org/0000-0001-7560-6320)
- Claire Louise Wood (ORCID: https://orcid.org/0000-0002-6084-5174)
- Shima Abdelrahman
- Talat Mushtaq (ORCID: https://orcid.org/0000-0002-9890-7369)
- Sze Choong Wong (ORCID: https://orcid.org/0000-0003-2845-6555)
- Vrinda Saraff (ORCID: https://orcid.org/0000-0003-3601-8942)
- Raja Padidela (ORCID: https://orcid.org/0000-0002-3350-9896)
Institutions
- Leeds Teaching Hospitals NHS Trust (GB)
- Royal Hospital for Children (GB)
- University of Manchester (GB)
- Southampton Children's Hospital (GB)
- Great North Children's Hospital (GB)
- Birmingham Women’s and Children’s NHS Foundation Trust (GB)
- Royal Manchester Children's Hospital (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1515/jpem-2025-0039
- Citations
- 2
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61