Reduction of non-classical monocytes that suppress interferon-α in patients with systemic lupus erythematosus
Our study demonstrated that the number of circulating non-classical monocytes, which has been shown to have the ability to suppress IFN-α production, was decreased in SLE patients, and this might be related to the excess IFN signature in SLE patients.
Authors
- Naohiro Hashimoto (ORCID: https://orcid.org/0000-0002-9231-8053)
- Shigeru Iwata
- Naoaki Ohkubo (ORCID: https://orcid.org/0000-0003-2265-4104)
- Jaafar El Annan
- Shingo Nakayamada (ORCID: https://orcid.org/0000-0002-2209-8454)
- Yoshiya Tanaka
- Yusuke Miyazaki (ORCID: https://orcid.org/0009-0006-8032-0136)
- Kei Sakata
- Akina Ishii
Institutions
- University of Occupational and Environmental Health Japan (JP)
- Mitsubishi Tanabe Pharma Corporation
Publication Details
- Journal
- Clinical and Experimental Rheumatology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.55563/clinexprheumatol/ziktdx
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00