Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study
The findings indicate a trend toward macular thinning and retinal microcirculatory dysfunction in the PTC patients, and these changes may be related to chronic inflammation and immune dysregulation secondary to cancer progression. OCT and OCT angiography show potential as noninvasive tools for detecting subclinical retinal abnormalities in PTC patients, and retinal alterations may serve as a surrogate marker for systemic inflammation. However, further studies are needed to address confounders and establish causality.
Authors
- Chaoran Lv
- Z D Zhang
- T Liu
- Rong-Xia Cao
- Haiyan Liu (ORCID: https://orcid.org/0000-0002-2500-4601)
- Yanjie Li (ORCID: https://orcid.org/0000-0001-7750-757X)
- Lulu Shi (ORCID: https://orcid.org/0000-0002-4761-2165)
- Zengyu Zhang (ORCID: https://orcid.org/0000-0001-5333-9911)
Institutions
- Shanxi Medical University (CN)
- Jinzhong University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1167/iovs.66.4.73
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanxi Scholarship Council of China