Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

The findings indicate a trend toward macular thinning and retinal microcirculatory dysfunction in the PTC patients, and these changes may be related to chronic inflammation and immune dysregulation secondary to cancer progression. OCT and OCT angiography show potential as noninvasive tools for detecting subclinical retinal abnormalities in PTC patients, and retinal alterations may serve as a surrogate marker for systemic inflammation. However, further studies are needed to address confounders and establish causality.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-04-24
DOI
https://doi.org/10.1167/iovs.66.4.73
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00

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OCT
article

Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

Chaoran Lv, Z D Zhang, T Liu, Rong-Xia Cao et al.
Investigative Ophthalmology & Visual Science
Glaucoma and retinal disorders
article

Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

Chaoran Lv, Z D Zhang, T Liu, Rong-Xia Cao, Haiyan Liu, Yanjie Li, Lulu Shi, Zengyu Zhang
article en

Abstract

The findings indicate a trend toward macular thinning and retinal microcirculatory dysfunction in the PTC patients, and these changes may be related to chronic inflammation and immune dysregulation secondary to cancer progression. OCT and OCT angiography show potential as noninvasive tools for detecting subclinical retinal abnormalities in PTC patients, and retinal alterations may serve as a surrogate marker for systemic inflammation. However, further studies are needed to address confounders and establish causality.

Investigative Ophthalmology & Visual ScienceVol. 66(4)
Shanxi Medical University (CN), Jinzhong University (CN), First Hospital of Shanxi Medical University (CN)
National Natural Science Foundation of China, Shanxi Scholarship Council of China
Openalex Percentile: Top 86%
Glaucoma and retinal disorders
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