Longitudinal variability of blood eosinophils impact lung function decline in the general population
BEC is not a static biomarker; longitudinal variability predicts changes in lung function. Current guidelines rely on single time-point BEC measurements, but our findings suggest that repeated assessments and the use of thresholds to determine normal BEC variability over time may better guide treatment decisions in high-risk patients.
Authors
- Oliver Helk
- Robab Breyer‐Kohansal (ORCID: https://orcid.org/0000-0001-5850-5923)
- Marie‐Kathrin Breyer (ORCID: https://orcid.org/0000-0003-2086-8483)
- Charmaine J. M. Lim (ORCID: https://orcid.org/0009-0007-9398-9629)
- Emiel F.�M. Wouters (ORCID: https://orcid.org/0000-0002-9186-575X)
- Sylvia Hartl (ORCID: https://orcid.org/0000-0002-0734-0070)
Institutions
- Sigmund Freud Privatuniversität Wien (AT)
- Maastricht University Medical Centre (NL)
- Vienna General Hospital (AT)
- Maastricht University (NL)
- Klinik Hietzing (AT)
- Ludwig Boltzmann Institute for Lung Vascular Research (AT)
- Ludwig Boltzmann Institute for Digital Health and Prevention (AT)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1183/23120541.00368-2025
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00