Resveratrol inhibits the progression of oral squamouscell carcinoma through Norad/Igf2bp2/Pdk1 pathway and remodeling glucose metabolism reprogramming

Resveratrol inhibits OSCC proliferation, particularly in CAL-27 cells. It affects NORAD, IGF2BP2, and PDK1 pathways, altering cell cycle protein expression and causing S and G2/M phase arrest.

Authors

Yicong Lin (ORCID: https://orcid.org/0000-0002-3994-4637)
Rongrong Zhang (ORCID: https://orcid.org/0009-0007-9427-3729)
Jinjing Guo

Institutions

Zhejiang Chinese Medical University (CN)

Publication Details

Journal: Discover Oncology
Published: 2025-04-24
DOI: https://doi.org/10.1007/s12672-025-02363-z
Citations: 1
Primary Topic: Cancer-related molecular mechanisms research
Type: article
Field-Weighted Citation Impact: 0.94

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article

Resveratrol inhibits the progression of oral squamouscell carcinoma through Norad/Igf2bp2/Pdk1 pathway and remodeling glucose metabolism reprogramming

Yicong Lin, Rongrong Zhang, Jinjing Guo

Apr 24, 2025

1 citations

Discover Oncology

Cancer-related molecular mechanisms research

0.94

article

Resveratrol inhibits the progression of oral squamouscell carcinoma through Norad/Igf2bp2/Pdk1 pathway and remodeling glucose metabolism reprogramming

Yicong Lin, Rongrong Zhang, Jinjing Guo

April 24, 2025article en

1 citations

Abstract

Resveratrol inhibits OSCC proliferation, particularly in CAL-27 cells. It affects NORAD, IGF2BP2, and PDK1 pathways, altering cell cycle protein expression and causing S and G2/M phase arrest.

Discover OncologyVol. 16(1)

Zhejiang Chinese Medical University (CN)

Zero hunger

Openalex Percentile: Top 26%

Cancer-related molecular mechanisms research

0.94

DOI Open Access PDF OpenAlex

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Resveratrol inhibits the progression of oral squamouscell carcinoma through Norad/Igf2bp2/Pdk1 pathway and remodeling glucose metabolism reprogramming — Yicong Lin, Rongrong Zhang, et al. · Discover Oncology (2025) | TGRS Research Map | TGRS