Efficacy, Safety, and Drug Survival During the First Year of Biologic Therapy for Psoriasis in Elderly Versus Younger Patients

The efficacy of biological treatment was comparable between older and younger patients. Despite older people having more comorbidities, SAEs did not increase in this age group. Nonetheless, the survival rate of older patients was notably lower during the treatment period, especially when adalimumab was administered.

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Institutions

Publication Details

Journal
International Journal of Dermatology
Published
2025-04-24
DOI
https://doi.org/10.1111/ijd.17814
Citations
3
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
2.39

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article

Efficacy, Safety, and Drug Survival During the First Year of Biologic Therapy for Psoriasis in Elderly Versus Younger Patients

M Salavec, Simona Vachatova, M Tichý, Martina Kojanová et al.
3 citations
International Journal of Dermatology
Psoriasis: Treatment and Pathogenesis
2.39
article

Efficacy, Safety, and Drug Survival During the First Year of Biologic Therapy for Psoriasis in Elderly Versus Younger Patients

M Salavec, Simona Vachatova, M Tichý, Martina Kojanová, Alena Machovcová, Miroslav Nečas, Martin Cetkovsky, Jan Hugo, Simona Tivadar, Filip Rob, Natalie Kunesova, Tereza Sobotkova, Pavlina Prikrylova, Zdenka Kysilka
article en
3 citations

Abstract

The efficacy of biological treatment was comparable between older and younger patients. Despite older people having more comorbidities, SAEs did not increase in this age group. Nonetheless, the survival rate of older patients was notably lower during the treatment period, especially when adalimumab was administered.

International Journal of DermatologyVol. 64(8)
Charles University (CZ), Masaryk University (CZ), University Hospital in Motol (CZ), University Hospital Olomouc (CZ), University Hospital Hradec Králové (CZ), University Hospital Kralovske Vinohrady (CZ), Palacký University Olomouc (CZ)
Ministerstvo Zdravotnictví Ceské Republiky
Good health and well-being
Openalex Percentile: Top 12%
Psoriasis: Treatment and Pathogenesis
2.39
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Efficacy, Safety, and Drug Survival During the First Year of Biologic Therapy for Psoriasis in Elderly Versus Younger Patients — M Salavec, Simona Vachatova, et al. · International Journal of Dermatology (2025) | TGRS Research Map | TGRS