Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis
The findings of this study indicate that CXCR4 may serve as a potential genetic marker for DVT, with MIF - (CD74 + CXCR4) potentially implicated in the regulatory mechanisms underlying DVT.
Authors
- Yang-yi-jing Wang
- Dong-yang Luo
- Zixuan Wu (ORCID: https://orcid.org/0000-0002-2993-9949)
- Guoshan Bi (ORCID: https://orcid.org/0000-0001-7661-6977)
- Liming Deng (ORCID: https://orcid.org/0000-0002-8862-9967)
- Xianpeng Dai (ORCID: https://orcid.org/0000-0001-9815-294X)
- Zhihe Deng
- Guozuo Xiong
- Mingjun Jiang (ORCID: https://orcid.org/0000-0002-4228-4916)
- Bin Pan (ORCID: https://orcid.org/0000-0001-9596-8871)
- Dongdong Ning (ORCID: https://orcid.org/0000-0001-8015-0831)
- Jie Chen (ORCID: https://orcid.org/0009-0003-2727-0289)
Institutions
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-04-24
- DOI
- https://doi.org/10.3389/fgene.2025.1551879
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94