Psychosocial Impact of Knee Joint Pain and Experimental Analysis of Platelet-Rich Plasma (PRP) Treatment

Knee joint pain is one of the primary causes of mobility impairments and reduced quality of life globally. With the aging of the population and the increase in sports-related injuries, the incidence of knee joint pain has risen significantly. Common types of knee joint pain are classified as either pathological or physiological, encompassing conditions such as osteoarthritis, synovitis, meniscus injuries, cartilage wear, and ligament tears. These chronic and progressive pains exert negative consequences and impacts on patients’ personal psychology, social activities, family burdens, and socio-economic status. In recent years, Platelet-Rich Plasma (PRP) therapy, an innovative biological treatment, has demonstrated remarkable effectiveness in treating numerous knee conditions. PRP is a biological agent prepared by extracting and concentrating platelets from the patient’s own blood. It’s rich in growth factors and cytokines such as PDGF, VEGF, EGF, SDF1-α, etc., and has the potential to promote tissue repair and regeneration. This study not only focuses on the physiological improvements achieved through PRP therapy but also delves into its positive effects on patients’ psychological state and the synergistic role of psychological interventions in this process. Psychological interventions, including psychological education and cognitive-behavioral therapy, can enhance patients’ treatment compliance, reduce pain perception, facilitate the rehabilitation process, and improve psychological well-being. The combination of PRP therapy and psychological interventions provides a more comprehensive and effective treatment regimen for patients with knee joint pain, potentially enhancing their quality of life and alleviating socio-economic burdens.