Evaluation of Early-onset Sepsis Calculator Among Clinically Well Late-preterm and Term Neonates: A Prospective Cohort Study

With only 1 culture-proven EOS case among 1157 neonates, the sample size was a limitation to draw conclusions on the safety of implementing the SRC. However, the study provided valuable insights, and in our setting, the KPNC SRC could offer an alternative approach in predicting the risk of EOS among term and near-term neonates clinically well at birth, potentially reducing the use of empirical antibiotics, though with a slight increase in laboratory evaluations. No risk assessment tool is flawless, emphasizing the importance of educating parents on warning signs of EOS.