Mechanosynthesis of β-Naphthol Derivatives via Triflic Anhydride-Mediated Reaction of Arylacetic Acids with Arylalkynes
The mechanosynthesis of β-naphthol derivatives was accomplished through triflic anhydride-mediated cyclization reactions of arylacetic acids with arylalkynes in moderate to good yields by ball milling at room temperature. The present protocol featured solvent-free and simple conditions, a short reaction time, and easily available and inexpensive reagents.
Authors
- Xu-Ling Xia
- Guan‐Wu Wang (ORCID: https://orcid.org/0000-0001-9287-532X)
- Jun-Shen Chen
- L. Li (ORCID: https://orcid.org/0000-0001-6411-6107)
- Lifeng Guo (ORCID: https://orcid.org/0000-0002-0253-3447)
Institutions
- University of Science and Technology of China (CN)
- Hefei Normal University (CN)
- State Key Laboratory of Applied Organic Chemistry
- Anhui Normal University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1021/acs.joc.5c00204
- Primary Topic
- Chemical synthesis and alkaloids
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China