ASO Author Reflections: Rethinking Surgical Strategies for Pediatric Liver Tumors with Vascular Involvement: Resection with Vascular Reconstruction as an Alternative to Transplantation

PASTLiver tumors in children that present as large, centrally located masses involving the hepatic venous confluence or the inferior vena cava (IVC), pose significant surgical challenges. 1 In such cases, some centers may favor liver transplantation (LT) due to the complexity of liver resection with vascular reconstruction and the risk of local recurrence. 2,3However, LT carries notable drawbacks, including limited organ availability, the need for lifelong immunosuppression, and potential long-term complications. 4Given these concerns, organ-preserving alternatives are particularly desirable in pediatric patients whenever feasible and oncologically effective.While vascular reconstruction has been investigated in adult liver surgery, its outcomes in pediatric liver tumor surgery remain unstudied.Our study aimed to assess the safety, feasibility, and oncological outcomes of extended liver resections with vascular reconstruction of the hepatic veins and/or the IVC as an alternative to LT in select cases. 5

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Publication Details

Journal
Annals of Surgical Oncology
Published
2025-04-24
DOI
https://doi.org/10.1245/s10434-025-17312-x
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
0.00

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ASO Author Reflections: Rethinking Surgical Strategies for Pediatric Liver Tumors with Vascular Involvement: Resection with Vascular Reconstruction as an Alternative to Transplantation

Juri Fuchs, Sophie Branchereau
1 links
Annals of Surgical Oncology
Genetic and Kidney Cyst Diseases
article

ASO Author Reflections: Rethinking Surgical Strategies for Pediatric Liver Tumors with Vascular Involvement: Resection with Vascular Reconstruction as an Alternative to Transplantation

Juri Fuchs, Sophie Branchereau
article en

Abstract

PASTLiver tumors in children that present as large, centrally located masses involving the hepatic venous confluence or the inferior vena cava (IVC), pose significant surgical challenges. 1 In such cases, some centers may favor liver transplantation (LT) due to the complexity of liver resection with vascular reconstruction and the risk of local recurrence. 2,3However, LT carries notable drawbacks, including limited organ availability, the need for lifelong immunosuppression, and potential long-term complications. 4Given these concerns, organ-preserving alternatives are particularly desirable in pediatric patients whenever feasible and oncologically effective.While vascular reconstruction has been investigated in adult liver surgery, its outcomes in pediatric liver tumor surgery remain unstudied.Our study aimed to assess the safety, feasibility, and oncological outcomes of extended liver resections with vascular reconstruction of the hepatic veins and/or the IVC as an alternative to LT in select cases. 5

Annals of Surgical OncologyVol. 32(7)
Heidelberg University (DE), Université Paris-Saclay (FR), Assistance Publique – Hôpitaux de Paris (FR), Bicêtre Hospital (FR)
Universität Heidelberg
Good health and well-being
Openalex Percentile: Top 90%
Genetic and Kidney Cyst Diseases
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ASO Author Reflections: Rethinking Surgical Strategies for Pediatric Liver Tumors with Vascular Involvement: Resection with Vascular Reconstruction as an Alternative to Transplantation — Juri Fuchs, Sophie Branchereau · Annals of Surgical Oncology (2025) | TGRS Research Map | TGRS