CHIP’ing Signal from Noise in Liquid Biopsy
The presence of clonal hematopoiesis in cell-free DNA analysis can distort the interpretation of results and influence cancer treatment decisions. This CCR Translations discusses the importance of distinguishing the origin of cell-free DNA variants as tumoral or hematopoietic and its potential clinical implications. See related article by Magee et al., p. 2710.
Authors
- Jean‐Baptiste Micol (ORCID: https://orcid.org/0000-0003-0934-294X)
- Elsa Bernard (ORCID: https://orcid.org/0000-0002-2057-7187)
Institutions
- Inserm (FR)
- Université Paris-Saclay (FR)
- Institut Gustave Roussy (FR)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-0569
- Citations
- 3
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Pfizer
- Servier