The PVT1-214/miR-671-5p/SLC45A4 signaling axis regulates cell proliferation in human gastric cancer
The present work revealed the candidate ceRNA regulatory pathway by which PVT1-214 regulates SLC45A4 expression in GC cells, which is achieved through competitive binding to endogenous miR-671-5p. The results of this study can shed novel light on new molecular targets for treating GC.
Authors
- Yongxiang Li (ORCID: https://orcid.org/0000-0002-6087-4135)
- Weitong Zhang (ORCID: https://orcid.org/0000-0001-6254-161X)
- Huizhen Wang (ORCID: https://orcid.org/0000-0001-5588-5545)
- Yong Zhao (ORCID: https://orcid.org/0000-0001-9282-9980)
- Wei Yan (ORCID: https://orcid.org/0000-0002-5835-0308)
Institutions
- Wannan Medical College (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1186/s12957-025-03805-2
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Anhui Medical University