Evaluation of the antiproliferative, cytotoxic and phytochemical properties of Zimbabwean medicinal plants used in cancer treatment
This study demonstrates that Agelenthus pungu, Carissa edulis, Leonotis ocymifolia, Leucas martinicensis and Viscum verrucosum have antiproliferative activity against Jurkat T and HL60 cell lines. Viscum verrucosum was the most potent. These findings emphasise the importance of medicinal plants as well as their potential use as sources of novel compounds in anticancer drug discovery.
Authors
- Stanley Mukanganyama (ORCID: https://orcid.org/0000-0001-6071-6439)
- Sigcono Mlilo
- Simbarashe Sithole (ORCID: https://orcid.org/0000-0002-3619-229X)
- S. Sibanda
- Yogehkumar S Naik
Institutions
- National University of Science and Technology (ZW)
- African Institute of Biomedical Science and Technology (ZW)
- Department of Research and Specialist Services (ZW)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1186/s12906-025-04883-1
- Citations
- 2
- Primary Topic
- Ethnobotanical and Medicinal Plants Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- National University of Science and Technology