Hydrogel Design to Understand and Guide 3D Cell Migration
Cell movement is important in both healthy and diseased tissues. An understanding of how cells migrate and the development of methods to control their migration can be utilized to improve patient therapies in the future in applications such as tissue repair and regeneration. Hydrogels are water-swollen materials that mimic many features of tissues. This allows their use to understand how cells respond to various features in their environment, as well as for therapeutic materials in tissue repair. This review highlights advances on these topics.
Authors
- Robert L. Mauck (ORCID: https://orcid.org/0000-0002-9537-603X)
- Jason A. Burdick (ORCID: https://orcid.org/0000-0002-2006-332X)
- Karen Xu (ORCID: https://orcid.org/0000-0003-4418-9194)
Institutions
- University of Colorado Boulder (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Regenerative Engineering and Translational Medicine
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1007/s40883-025-00395-z
- Primary Topic
- Planarian Biology and Electrostimulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- University of Pennsylvania
- National Institutes of Health
- Division of Civil, Mechanical and Manufacturing Innovation
- Penn Center for Musculoskeletal Disorders