In vivo assessment of the effect of gel containing lactic acid and glycogen on vaginal microbiota and pH of asymptomatic women of reproductive age
The lactic acid-containing gel demonstrated a significant reduction in vaginal pH and Nugent scores in asymptomatic women, indicating possible improvement in vaginal health, that needs to be confirmed in a placebo-controlled study. Although the intervention did not influence microbial diversity and the type of vaginal microbiota at the end of the study, it was able to reduce the prevalence of some taxonomic groups after intervention with the vaginal gel.
Authors
- Adriana Bittencourt Campaner (ORCID: https://orcid.org/0000-0002-3044-3019)
- Giulia Marchetti (ORCID: https://orcid.org/0000-0001-6633-3340)
- ANA CAROLINA ALVES ROSÁRIO DE SICA
- Bianca Luise Teixeira (ORCID: https://orcid.org/0000-0002-0888-2795)
- Flavia Salomão d' Avila Curi (ORCID: https://orcid.org/0000-0001-5775-5867)
- G. Dias
Institutions
- Faculdade de Ciências Médicas da Santa Casa de São Paulo (BR)
- Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina (BR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1371/journal.pone.0321737
- Citations
- 2
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 2.37