Long-term alterations of collagen reconstruction and basement membrane regeneration after corneal full-thickness penetrating injury in rabbits
Following full-thickness corneal injury, persistent fibrosis within the posterior stroma appears to be primarily responsible for the persistence of corneal scarring. Notably, regeneration of the EBM coincides with remodeling of the anterior stroma, whereas incomplete regeneration of DM is associated with posterior stromal fibrosis.
Authors
- Xia Li (ORCID: https://orcid.org/0000-0001-9945-259X)
- Sumei Li (ORCID: https://orcid.org/0000-0002-4793-3161)
- Luting Xie
- Jingjing Chen (ORCID: https://orcid.org/0000-0001-7535-8494)
- Na Meng (ORCID: https://orcid.org/0000-0002-5234-8872)
- Yuqing Luo (ORCID: https://orcid.org/0000-0002-0550-2128)
- Shuifang Xiao
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1371/journal.pone.0320802
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- National Natural Science Foundation of China