Plasma trimethylamine N-oxide concentration and all-cause mortality in kidney transplant recipients
Plasma TMAO decreases sharply after kidney transplantation, without reaching healthy controls levels. A higher plasma TMAO concentration was independently associated with an increased mortality risk in KTR. Further research is warranted to assess whether accounting for gut dysbiosis and TMAO could improve clinical outcomes in KTR.
Authors
- António W. Gomes‐Neto (ORCID: https://orcid.org/0000-0002-4398-4877)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Daan Kremer (ORCID: https://orcid.org/0000-0003-0011-115X)
- Manuela Yepes-Calderón (ORCID: https://orcid.org/0000-0002-4693-5974)
- Eva Corpeleijn (ORCID: https://orcid.org/0000-0002-2974-3305)
- Robin P.F. Dullaart (ORCID: https://orcid.org/0000-0003-4520-1239)
- Tim J. Knobbe (ORCID: https://orcid.org/0000-0003-3246-3192)
- Martin H. de Borst (ORCID: https://orcid.org/0000-0002-4127-8733)
- F Cambronero Sanchez (ORCID: https://orcid.org/0000-0002-9151-4271)
- Margery A Connelley
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- LabCorp (United States) (US)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1093/ndt/gfaf071
- Citations
- 4
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.94